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The NXT TFF system by PharmNXT Biotech is a system that’s perfect for running fully automated UF/DF processes at high capacity. It can handle any volume between 20L and 500L (200 g to 2.5 kg), and the compact system, has a low hold-up volume and the capacity to accommodate cassettes with surface area ranging from 0.5 to 2.5 m2
System Concept:
The NXT TFF System is a combination of hardware, a control system and single-use flow kits that work together to create a system that provides ease of use. It has been proven to run automated process sequences for TFF processes — while keeping sensors and instruments within reach.
- The NXT TFF System facilitates the automated processing of batch volumes from 20 to 500 L of monoclonal antibodies, recombinant proteins and vaccines processes.
- The single-use sensors provide the means to fully monitor and control the process
Typical applications
- Cell harvesting/clarification
- Recombinant protein concentration
- Vaccine concentration/purification
- Monoclonal antibody clarification/concentration
- Plasma purification/concentration
User-Friendly Software:
The control unit uses a simple, user-friendly interface via the touchscreen for data input and programming commands. The system is shielded from unauthorized access with password protection (four levels), and all events and actions (alarms, process steps, manual commands, etc.) are recorded in accordance with cGMP guidelines. The program allows you to operate the system manually or automatically.
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