Single-use technology continues to be adopted for many areas of bioprocessing. The use of automation provides additional benefits in manufacturing such as consistency in product quality, reduced labor costs, and reduction of operator errors.
The NXTmfilt system is designed for use in many areas of bioprocessing such as:
- Sterile filtration
- Bioburden reduction
- Depth filtration
- Virus filtration
- Media and buffer preparation
- Membrane chromatography
- pH adjustment
- Virus inactivation
- Final formulation and filling
The systems are designed to automate all of the steps needed for pH adjustments and virus inactivation, with fully automated addition of acid & base stock solutions.
A large selection of pre-designed manifolds is available, which ensures that it will suit a wide range of applications. A specially designed manifold selection tool helps identify the most suitable manifold for your application from this assortment.
A choice between sensors and connectors, as well as tubing type, provides an easy way to configure a system without any guesswork or mistakes when selecting flow paths: no other system offers such extensive standard configurations!
The system is designed to automatically monitor multiple parameters and the following sensors can be selected:
- Pressure (inlet, between filters, outlet single-use sensors)
- pH (reusable probe in mixer)
- Flow (inlet single-use sensors)
- Conductivity (reusable probe in mixer or single-use sensor on outlet)
- UV (outlet single-use sensors)
- Mass (via load cell connection)
PharmNXT Biotech supports customers from the design to the execution phase of a new and existing production facility with the most comprehensive support program, that ensures the successful design, implementation, and validation of the manufacturing facility. PharmNXT Biotech offers end-to-end solutions for Pharmaceutical, Biopharmaceutical and Vaccine manufacturing.
The NXT TFF system by PharmNXT Biotech is a system that’s perfect for running fully automated UF/DF processes at high capacity. It can handle any volume between 20L and 500L (200 g to 2.5 kg), and the compact system, has a low hold-up volume and the capacity to accommodate cassettes with surface area ranging from 0.5 to 2.5 m2
NXTchrom is a range of configurable chromatography systems designed to meet all chromatography-based process requirements and the design can handle any column diameter. We use a proven platform that allows you to integrate different options into one core platform.
With a self-contained design, the NXTchrom System incorporates pumps, valves, and instruments in a single system. The system’s control cabinets include pneumatic and electric components, and the system can be controlled using an easy-to-use touch screen interface.
NXTmix is the next-generation levitation-based mixing technology designed to handle all your single-use mixing requirements from media & buffer preparation, intermediate process mixing, final formulation and filling application. Highly flexible and cGMP complaint system allows you to use volumes commonly used in manufacturing processes of up to 1000L.
KoNXT is a range of Single Use assemblies designed as per the process needs of the customer. The customized KoNXT assemblies are carefully designed with a high degree of process knowledge to eliminate operator error and reduce the risk of contamination, XELTA KoNXT Single Use Assemblies minimize process risk in sterile operations by employing proven flexible connections. Through XELTA KoNXT assemblies, we’re able to provide maximum flexibility by allowing you to connect a wide variety of tube sizes and connectors into one easy solution. Optimized for single-use applications, XELTA KoNXT assemblies allow PharmNXT Biotech Team to create assemblies tailored to your specific requirements that result in reduced process risk.