The NXTmfilt system is a versatile and automated solution for bioprocessing needs. It incorporates single-use technology and advanced engineering design to ensure reliability and minimize operator errors. With its flexibility, it can handle various processes such as sterile filtration, virus filtration, pH adjustment, and more. The system’s high degree of automation enables precise control over key parameters, while its monitoring capabilities allow real-time data analysis. Overall, the NXTmfilt system optimizes bioprocessing operations for consistent product quality and reduced labor costs.
Automated Bioprocessing System
The NXTmfilt system is a versatile tool for bioprocessing, ensuring the quality and safety of biopharmaceutical products. It offers flexible solutions for sterile filtration, clarification, bioburden reduction, virus filtration, and particle removal. With advanced features, it optimizes filtration efficiency, control parameters, and accommodates different filter types and sizes. Its scalability allows integration into existing setups, meeting evolving needs. The system improves operational efficiency, reduces costs, and minimizes manual interventions through automation and real-time monitoring. It boosts productivity, shortens processing times, and maximizes resource utilization.
1) Easy Configuration
PharmNXT Biotech supports customers from the design to the execution phase of a new and existing production facility with the most comprehensive support program, that ensures the successful design, implementation, and validation of the manufacturing facility. PharmNXT Biotech offers end-to-end solutions for Pharmaceutical, Biopharmaceutical and Vaccine manufacturing.
2) Design:
The systems are designed to automate all of the steps needed for pH adjustments and virus inactivation, with fully automated addition of acid & base stock solutions.
A large selection of pre-designed manifolds is available, which ensures that it will suit a wide range of applications. A specially designed manifold selection tool helps identify the most suitable manifold for your application from this assortment.
A choice between sensors and connectors, as well as tubing type, provides an easy way to configure a system without any guesswork or mistakes when selecting flow paths: no other system offers such extensive standard configurations!
DOWNLOAD DATASHEET (PDF)
MORE SOLUTIONS
NXTtff
The NXT TFF system by PharmNXT Biotech is a system that’s perfect for running fully automated UF/DF processes at high capacity. It can handle any volume between 20L and 500L (200 g to 2.5 kg), and the compact system, has a low hold-up volume and the capacity to accommodate cassettes with surface area ranging from 0.5 to 2.5 m2
Chromatography Resins (Purolite)
The purification of commercially-available monoclonal antibodies (mAbs) on the market today is typically performed in three chromatography steps. Purolite offer industry-leading solutions for each step.
Protein A Affinity Chromatography
A Protein A affinity resin is utilized as an initial antibody capture step. Praesto Protein A resins deliver exceptionally high purity (>99%) and yield in a single, efficient step.
Cation Exchange Chromatography
A Sulphopropyl- (SP) functionalized cation exchange resin in ‘bind and elute’ mode is used to remove aggregates and HCP (Host Cell Proteins).
Anion Exchange Chromatography
A Quarternary Amine (Q) functionalized anion exchange resin is used in ‘flow-through’ mode to remove trace contaminates and ensure sufficient viral clearance.
NXTmfilt
Single-use technology continues to be adopted for many areas of bioprocessing. The use of automation provides additional benefits in manufacturing such as consistency in product quality, reduced labor costs, and reduction of operator errors.